Vol. 13 No. 1 (2021): Archives of Public Health
Case Report

Microbiological aspects of pulmonary infection with Actinomyces odontolyticus - case report

Snezana Ivic-Kolevska
Private Health Institution “Re-Medika”, Skopje, Republic of North Macedonia
Andreja Arsovski
Private Health Institution “Re-Medika”, Skopje, Republic of North Macedonia

Published 2021-06-20

Keywords

  • actinomycosis,
  • penicillin,
  • pulmonary infection

How to Cite

1.
Ivic-Kolevska S, Arsovski A. Microbiological aspects of pulmonary infection with Actinomyces odontolyticus - case report. Arch Pub Health [Internet]. 2021 Jun. 20 [cited 2021 Sep. 26];13(1):114-21. Available from: https://id-press.eu/aph/article/view/5936

Abstract

Pulmonary actinomycosis is a rare and uncommon invasive bacterial disease. We are presenting a case report of 45 year old male patient with severe acute pneumonia with pleural effusion, presenting with fever, fatigue, productive cough, chest pain, dyspnea and swelling on both legs. Microbiological findings showed an isolation of anaerobic bacterium Actinomyces odontolyticus. The antibiogram showed sensitivity on penicillin and penicillin preparations, cephalosporins and carbapenems. There was an intermediate sensitivity on quinolones and there was a resistance on lincosamins and aminoglycosides. Our patient was treated with operation and received appropriate antibiotic therapy, after which there was a very good improvement, both clinically and on control native lung RTGs. This disease has excellent prognosis with early detection and proper treatment. Penicillin is the drug of choice for treatment of pulmonary actinomycosis.

Downloads

Download data is not yet available.

References

  1. Wong VK, Turmezei TD, Weston VC. Actinomycosis BMJ. 2011;53:343.
  2. Valour F, Sénéchal A, Dupieux C, Karsenty J, Lustig S, Breton P, et al. Actinomycosis: etiology, clinical features, diagnosis, treatment, and management. Infect Drug Resist 2014;7:183-197.
  3. Cone LA, Leung MM, Hirschberg J. Actinomyces odontolyticus bacteremia. Emerg Infect Dis 2003;9(12):1629-32.
  4. Felz MW, Smith MR. Disseminated actinomycosis: multisystem mimicry in primary care. South Med J 2003;96(3):294-9.
  5. Mandell GL, Bennett JE, Dolin R, editors. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, PA: Churchill Livingstone Elsevier; 2010.
  6. Kakuta R, Hidaka H, Yano H, Miyazaki H, Suzaki H, Nakamura Y, et al. Identification of Actinomyces meyeri actinomycosis in middle ear and mastoid by 16S rRNA analysis. J Med Microbiol 2013; 62:1245–48.
  7. Mehta D, Statham M, Choo D. Actinomycosis of the temporal bone with labyrinthine and facial nerve involvement. Laryngoscope 2007;117:1999–2001.
  8. Oostman O, Smego RA. Cervicofacialactinomycosis: diagnosis and management. Curr Infect Dis Rep 2005;7:170–4.
  9. Mabeza GF, Macfarlane J. Pulmonary actinomycosis. Eur Respir J 2003;21(3): 545- 51.
  10. Lee JP, Rudoy R. Pediatric thoracic actinomycosis. Hawaii Med J 2003;62(2): 30-2.
  11. Brook I. Actinomycosis: diagnosis and management. South Med J 2008;101 (10):1019-23.
  12. Farrokh D, Rezaitalab F, Bakhshoudeh B. Pulmonary actinomycosis with endobronchial involvement:A case report and literature review. Tanaffos 2014; 13(1): 52-6.
  13. Choi J, Koh WJ, Kim TS, Lee KS, Han J, Kim H, et al. Optimal duration of IV and oral antibiotics in the treatment of thoracic actinomycosis. Chest 2005;128(4): 2211-7.
  14. Endo S, Murayama F, Yamaguchi T, Yamamoto S, Otani S, Saito N, et al. Surgical considerations for pulmonary actinomycosis. Ann ThoracSurg 2002;74(1): 185-90.
  15. Boudaya MS, Smadhi H, Marghli A, Mouna M, Charmiti F, Ismail O, et al. Surgery in thoracic actinomycosis. Asian CardiovascThorac Ann 2012;20(3): 314- 9.