Vol. 16 No. 1 (2024): Arch Pub Health
Public Health

Antimicrobial susceptibility of Salmonella enteritidis isolated in the period from 2020 to 2022 in the Shtip region

Kristina Sudiklieva
Faculty of Medical Sciences, Goce Delchev University, Shtip, Republic of North Macedonia
Golubinka Boshevska
Institute of Public Health of the Republic of North Macedonia; Faculty of Medical Sciences, Goce Delchev University, Shtip, Republic of North Macedonia
Marija Dimitrova
Center of Public Health, Shtip, Republic of North Macedonia
Dragan Kochinski
Institute of Public Health of the Republic of North Macedonia; Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Republic of North Macedonia

Published 2024-06-25

Keywords

  • infection,
  • food,
  • antimicrobial susceptibility,
  • Salmonella enteritidis

How to Cite

1.
Sudiklieva K, Boshevska G, Dimitrova M, Kochinski D. Antimicrobial susceptibility of Salmonella enteritidis isolated in the period from 2020 to 2022 in the Shtip region . Arch Pub Health [Internet]. 2024 Jun. 25 [cited 2024 Jul. 20];16(1). Available from: https://id-press.eu/aph/article/view/6123

Abstract

Bacteria of the genus Salmonella are widely distributed in nature. They can colonize different hosts and are the most common causes of intestinal infections in humans and animals. The main route of Salmonella transmission to humans is by contaminated food, or undercooked eggs and meat. The aim of this study was to analyze the antimicrobial susceptibility of Salmonella enteritidis, which was the most frequently isolated Salmonella in the Microbiological Laboratory of the Center of Public Health in Shtip. Materials and methods: A total of 1839 samples (12 rectal swabs and 1827 feces),   from persons suspect for salmonellosis in the region of Shtip were investigated for the period 2020 to 2022 year.  SS (Salmonella Shigella) agar, Rambach agar, and Selenit F media  were used for detection of Salmonella spp., and antimicrobial susceptibility testing of the isolated bacteria is performed  with disk diffusion method according EUCAST.  Results: Salmonella enteritidis is detected in 62 samples (3.37%), isolated strains of Salmonella enteritidis demonstrate high resistance to ampicillin 2 μg (37.09%), and multi-resistant strains (6.45%) were also detected.  Conclusion: The appearance of ampicillin and multi-resistant strains of Salmonella enteritidis in the samples analyzed in our study is a sign of concern and an alarm to initiate a change in the algorithm for the treatment of Salmonella enteritidis infections, especially with the use of fluoroquinolones and cephalosporins (of the third generation). It is recommended to introduce a system for the rational use of antimicrobials in human and veterinary health.

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