Abstract
Kinetics of tritium labeled coгtisol was performed in control rats, rats treated with Synacthen Depot and rats treated with Dexamethason i.m. Rats were injected with 2 microCuri directly into the lateral tail vein and timed samples were collected by aorta with heparin аѕ an anticoagulans.The results have shown that treatment with Synacthen led to а smaller half - time and turn over time. Treatment with Dexamethason led to an increase of half-time and decrease of turnover tme.
lt could be concluded that change of the functional state of adrenal gland influence the kinetics of radioactive labeled cortisol.- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
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