Vol. 12 No. 1 (2020): Archives of Public Health
Case Report

Two cases of non-syndromic congenital unilateral breast hypoplasia in one family

Marina Krstevska-Konstantinova
University Children's Hospital Skopje, North Macedonia
Konstandina Kuzevska-Maneva
University Children's Hospital, Skopje, North Macedonia
Elena Sukarova-Angelovska
University Children's Hospital, Skopje, North Macedonia
Ana Stamatova
University Children's Hospital, Skopje, North Macedonia
Velibor Tasic
University Children's Hospital, Skopje, North Macedonia
Zoran Gucev
University Children's Hospital, Skopje, Republic of North Macedonia
Julia Hаefele
Institute for Human Genetics, Technical University of Munich, Germany

Published 2020-02-20

Keywords

  • breast hypoplasia,
  • pubertal abnormalities,
  • micromastia

How to Cite

1.
Krstevska-Konstantinova M, Kuzevska-Maneva K, Sukarova-Angelovska E, Stamatova A, Tasic V, Gucev Z, Hаefele J. Two cases of non-syndromic congenital unilateral breast hypoplasia in one family. Arch Pub Health [Internet]. 2020 Feb. 20 [cited 2021 Dec. 7];12(1):58-61. Available from: https://id-press.eu/aph/article/view/4476

Abstract

Micromastia or breast hypoplasia is described as underdevelopment of a woman's mammary tissue. We present the case of a 15-year-old girl with unilateral micromastia, with familial predisposition. Ultrasound, hormonal, dysmorphic, cardiologic, genetic examinations and testing were performed. No mutation in the whole- exome sequencing was found, nor novel mutation. Some of these cases have been reported to be related to breаst cancer so further follow-up is mandatory. Therapy consists of surgical reconstruction of the affected breast. This is a rare condition and it requires a multidisciplinary approach.

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