Vol. 11 No. 1 (2019): Archives of Public Health
Clinical Science

Prevalence of metabolic syndrome among patients with schizophrenia in the Center for mental health – “Prolet”, Psychiatric Hospital -Skopje

Viktor Isjanovski
Center for Mental Health – “Prolet”, Psychiatric Hospital –Skopje, Republic of North Macedonia
Igor Isjanovski
Medical Faculty Skopje, University Ss Ciril and Methodius, Skopje, Republic of North Macedonia

Published 2019-04-06


  • schizophrenia,
  • metabolic syndrome,
  • risk factors

How to Cite

Исјановски В, Исјановски И. Prevalence of metabolic syndrome among patients with schizophrenia in the Center for mental health – “Prolet”, Psychiatric Hospital -Skopje. Arch Pub Health [Internet]. 2019 Apr. 6 [cited 2022 Jan. 19];11(1):95-103. Available from: https://id-press.eu/aph/article/view/2861


Schizophrenia has been associated with an increased risk of cardio-metabolic morbidity and mortality. Metabolic syndrome (MS), as a reliable predictor of cardiovascular morbidity and mortality, has also been shown to be more prevalent in patients with schizophrenia. In this study, we investigated the prevalence of  MS in a sample of patients with schizophrenia in the Center for Mental Health – “Prolet”, Psychiatric Hospital -Skopje, and the potential risk factors associated with it. Materials and methods: 50 patients with schizophrenia were recruited. All subjects provided a fasted sample of venous blood to measure high-density lipoprotein cholesterol (HDL-C), triglycerides and glucose levels. Weight, height and waist circumference were measured. Metabolic syndrome was defined according to the National Cholesterol Education Program Adult Tretmant Panel III (NCEP ATD III) criteria. Results: The prevalence of MS in patients with schizophrenia was 46.0%. Increasing body mass index (BMI) was identified to be significantly associated with the prevalence of MS. Conclusion: This study found a high prevalence of MS in patients with schizophrenia, and that BMI might be a risk factor in the development of MS. This information is clinically relevant as BMI is routinely measured in psychiatric practice today, and could be used to monitor for development of MS in schizophrenia.


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